The recent development in the field of science is well known. Nano-science is an important part of science development. Nano-particle plays vital role in present era because of its nano size and structural properties. It is well known that the field of Nanotechnology is exiting. It is imperative that national and international regulatory bodies cooperate closely not only with each other, but also with academia and industry, in developing harmonized terminology and standards, a framework for health and environmental risk assessment and, based on that, the necessary regulations and guidelines so that nanomaterials and nanotechnology can be developed responsibly. A large number of chemical reaction and process depends on nano-particles.